Freeze dryer system for strile,scalable manufacturing
Design and automation solutions for pharmaceutical, biotech,
food and laboratory freeze-drying applications
300+
FDA/cGMP-Compliant Projects Delivered
20+
Countries Served
17+
Years of Manufacturing Experience
30
Worldwide Partners
Pharmaceutical Freeze-Drying Systems
LYOMAC designs and manufactures freeze-drying systems for
biopharmaceutical, injectable and sterile production.
Our solutions support laboratory development, pilot-scale studies and commercial manufacturing, with chamber capacities of up to 1,000 L and automated loading options for high-throughput operations.Key solution areas:
Why Choose Lyomac
FDA / cGMP Full Compliance
Every LYOMAC lyophilization system is engineered to fully comply with FDA, cGMP and 21 CFR Part 11 regulations. We guarantee uncompromised data integrity, complete audit traceability and full regulatory readiness for global pharmaceutical and biotech markets.
Worldwide Local Service & Support
With an established service network spanning 30+ countries and regions globally, we provide end-to-end on-site installation, full IQ/OQ/PQ qualification & validation, as well as dedicated operational and maintenance training for your team.
20+ Years Specialized Lyophilization Expertise
For over two decades, LYOMAC has focused exclusively on pharmaceutical-grade freeze drying technology. We have delivered more than 500 high-performance freeze dryer systems worldwide, proven across complex biologic, API, and sterile drug production scenarios.
Energy-Saving Design & Fully Customized Engineering
Our advanced variable-frequency compressor technology reduces overall energy consumption by up to 30%. We tailor every unit’s design, chamber layout, and cycle parameters to perfectly match your unique product and lyophilization process specifications.
Intelligent SCADA Control Architecture
Our proprietary LYOPRO SCADA control platform delivers unmatched operational precision. It enables secured data integrity, tamper-proof audit trails, and reliable remote monitoring — fully validated to meet FDA 21 CFR requirements for regulated manufacturing environments.
End-to-End Full Lifecycle Partnership
We deliver far more than equipment. From early-stage process development, custom equipment selection, line integration, to lifetime after-sales optimization and upgrade — we provide a complete, one-stop total lyophilization lifecycle solution.
Commericial Freeze dryers
LYOPRO Commercial series production freeze dryers. All models come standard with integrated CIP/SIP systems, fully cGMP & FDA compliant for large-scale biopharmaceutical and sterile drug manufacturing.
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Pilot scade Freeze dryers
LYOPRO Pilot series lyophilizers support process development and small-batch production. Standard CIP/SIP configuration, ideal for formulation research, technology transfer and pre-commercial trials.
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Lab scade Freeze dryers
LYOLAB series laboratory freeze dryers are available in non-GMP and full cGMP-compliant versions. Designed for laboratory R&D, small sample testing, formulation screening and academic research.
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Applications for more industry and application
Pharma & Biologics
Sterile injectables, monoclonal antibodies, vaccines, blood products, cell and gene therapy intermediates.
Diagnostics & Laboratory
Antibody & enzyme reagents, nucleic acid kits, reference standards, biobanking and biological sample preservation.
APIs & Industrial Chemicals
Heat-sensitive APIs, pharmaceutical intermediates, specialty biochemicals and functional raw material precursors.
Food & Nutrition
Probiotics, freeze-dried fruits, vegetables, plant extracts and functional nutritional raw materials。
From the very beginning, LYOMAC has focused on advancing freeze-drying technology.
We deliver robust, stable lyophilization equipment fully compliant with cGMP, FDA and global regulatory standards.
We understand the challenges faced by startups and small-scale biotech enterprises. LYOMAC is committed to offering cost-effective, regulation-ready freeze dryers and automatic vial handling systems, allowing emerging companies to access high-standard lyophilization solutions without excessive investment.
Meanwhile, we maintain the consistent high quality expected of an international brand. Our complete product portfolio covers lab, pilot and industrial scale freeze dryers, together with integrated automatic loading & unloading systems. Supported by our worldwide service network, we provide full-lifecycle technical support to customers across the globe.
We sincerely invite global partners to cooperate with LYOMAC for mutual growth.
Robert Wang
CEO of Lyomac
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We Solve Your Freeze-Drying Challenges
Every product demands a distinct freeze-drying approach. Whether you’re scaling up production or optimizing an existing process, we work with you to design solutions that fit your exact needs.
Tell us about your product, capacity goals, and process specifications. Our experts, with over 15 years of deep freeze-drying experience, are ready to address your toughest challenges.
Reach out today to start the conversation…
Lyomac Pharma and Bio Freeze Dryers: Essential for Biopharmaceutical Stability and Production
Lyomac’s medical freeze dryers are indispensable in the biopharmaceutical sector, primarily used for stabilizing and long-term preservation of temperature-sensitive biological products, including vaccines, antibodies, diagnostic reagents, cell therapies, and protein drugs. Our machines are expertly designed to handle both vial injection preparations and Active Pharmaceutical Ingredients (APIs). Key features include precise temperature and vacuum control, which are crucial for maintaining the high biological activity of active ingredients and extending product shelf life. capacity range from 2~1,000 Liters.
Freeze Dryers for APIs & Pharmaceutical Intermediates: Aseptic & Anti-Oxidation Processing
Freeze Dryers for APIs & Pharmaceutical Intermediates: Aseptic & Anti-Oxidation Processing
LYOMAC provides professional lyophilization solutions for heat-sensitive APIs and pharmaceutical intermediates.
Featuring exclusive flip-shelf design without trays and built-in automatic liquid feeding system, our freeze dryers can be integrated with barrier isolators. The enclosed working environment guarantees aseptic operation and avoids oxidation of sensitive raw materials.
Vacuum low-temperature drying preserves ingredient activity and purity, supporting laboratory development, pilot testing and large-scale commercial production.
Precision Solutions for Nanomaterials and Delicate Item Preservation
Lyomac’s versatile freeze-drying technology also finds critical applications in highly specialized fields such as nanomaterials processing and the preservation of sensitive items, demonstrating the breadth of our engineering capabilities.
Our Service
Site service
Install, Commissioning & Start-up
Freeze drying process
Development & Optimization
Validation
SERVICE AND Support (DQ/IQ/OQ/PQ)
Conceptual design
Custom Design & Engineering Solutions
ABOUT LYOMAC
LYOMAC Company is dedicated to providing exceptional freeze-drying solutions for a wide range of industries. Whether you are in the pharmaceutical or active pharmaceutical ingredient (API) sectors requiring strict compliance with GMP, FDA, and other regulatory standards, or focused on innovative applications in food, nutritional products, and new materials, we offer tailored professional solutions. Our freeze-drying equipment boasts a powerful drying capacity of up to 2000 KG, meeting your diverse production needs. Select your industry today and contact our team of experts for comprehensive solutions and professional support.
80km from Shanghai Pudong Airport
Frequently Asked Questions
What is freeze-drying and why is it beneficial?
Freeze-drying, or lyophilization, is a dehydration process that works by freezing the product and then reducing the surrounding pressure to allow the frozen water to sublimate directly from the solid phase to the gas phase. This gentle process preserves the product’s structure, biological activity, and nutritional value, significantly extending its shelf life without using high heat.
Which industries can benefit from Lyomac freeze dryers?
Lyomac freeze dryers are highly versatile. We provide solutions for the biopharmaceutical industry (vaccines, APIs, injectables, diagnostics), the food & nutrition sector (fruits, vegetables, coffee, probiotics, functional foods), nanomaterials processing (preventing aggregation, preserving structure), and delicate item preservation (archival materials, biological specimens).
Do you offer freeze dryers for both small-scale R&D and large-scale production?
Yes, absolutely. Lyomac offers a comprehensive range of freeze dryer models, from compact laboratory and pilot-scale units ideal for research and development, to high-capacity industrial systems designed for continuous, large-volume manufacturing. We can tailor solutions to match your specific production scale and requirements.
How do Lyomac freeze dryers ensure product quality and integrity?
Our freeze dryers are engineered with advanced control systems that provide precise management of temperature, vacuum, and process parameters throughout the lyophilization cycle. This ensures optimal drying conditions, preventing degradation, maintaining product stability, and preserving the integrity and biological activity of your sensitive materials.
Are Lyomac freeze dryers compliant with international industry standards?
Yes, our medical freeze dryers are designed and manufactured to meet stringent international pharmaceutical standards, including GMP (Good Manufacturing Practices). We ensure our equipment supports your compliance needs across various regulated industries, providing documentation and validation support where required.
